The upper Potomac involves every part of the river that is not tidal.  That includes all waters from as far north as Cumberland, MD all the way to Little Falls, Washington DC.  It holds a variety of fishing opportunities as well as fish species, such as smallmouth bass, carp, sunfish, muskellunge, rock bass, catfish, and now the invasive northern snakehead.

Best Wading from Point of Rocks to Whites Ferry is 0.7 feet on the Point of Rocks Gauge.
Best Wading from Violets lock down to Turkey Run is 3.0 feet on the Little Falls Gauge.

How To Fish This Section Of River: